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  Vol. 101 No. 1, July 1970 TABLE OF CONTENTS
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Open Chest Pulsatile Left-Heart Bypass Without Anticoagulation

An Experimental Study

Edward J. Serres, MD; John C. German, MD; Akio Wakabayashi, MD; John E. Connolly, MD; Junichi Hirai, MD; Nrisingha D. Mukherjee, MD; Edward A. Stemmer, MD

AMA Arch Surg. 1970;101(1):18-20.


Abstract

A nonthrombogenic left-heart bypass system employing a pulsatile pump, porcine aortic valves, and polyurethan-polyvinyl-graphite-tetrahydrofuran-coated tubing to bypass the cross clamped thoracic aorta was evaluated in animal experiments. This system provided accurate control of proximal and distal aortic pressures and better tissue perfusion than nonpulsatile bypass techniques. Intraoperative and postoperative hemorrhage was markedly reduced because heparinization was not required. This nonthrombogenic pulsatile bypass would appear to be the method of choice to permit prolonged cross clamping of the thoracic aorta.



Author Affiliations

Irvine, Calif

From the Department of Surgery, University of California, Irvine, and the Veterans Administration Hospital, Long Beach, Calif.


Footnotes

Accepted for publication March 10, 1970.

Read before the sectional meeting of the Southern California Chapter of the American College of Surgeons, Coronado, Calif, Jan 17, 1970.

Reprint requests to Department of Surgery, University of California, Irvine, Calif 19664 (Dr. Connolly).



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