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Olga Jonasson, MD; Edward A. Lichter, MD; William M. Hamby, MD; Roger D. Smith, MD; Clarence L. Gantt, MD; Lloyd M. Nyhus, MD

AMA Arch Surg. 1970;101(2):219-225.

Abstract
Through studies of the distribution of HL-A antigens in a family and related donor selection on the basis of genotyping, excellent results have been achieved in cases of donor-recipient HL-A identity. Similar good results may be achieved in cases of donor-recipient monoallelic compatibility where the donor's nonshared allele is not associated with a major detectable HL-A antigen. In instances of monoallelic incompatibility where donor's nonshared allele is associated with a single detected HL-A antigen, the individual "strengths" of these antigens can be estimated on the basis of the clinical course of the recipient and studies of renal function and histology.

Author Affiliations
Chicago

From the departments of medicine (Drs. Hamby and Gantt), pathology (Dr. Smith), preventive medicine and community health (Dr. Lichter), and surgery (Drs. Jonasson and Nyhus), University of Illinois Medical Center, Chicago.

Footnotes
Accepted for publication April 15, 1970.

Read before the 27th annual meeting of the Central Surgical Association, Detroit, Feb 27, 1970.

Reprint requests to Department of Surgery, University of Illinois at the Medical Center, PO Box 6998, Chicago 60680 (Dr. Jonasson).

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