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Use of Living Donors in Kidney Transplantation in Man
Israel Penn, MD;
Charles G. Halgrimson, MD;
David Ogden, MD;
Thomas E. Starzl, PhD, MD
AMA Arch Surg. 1970;101(2):226-231.
Abstract
A series is presented of 238 living renal donors who have been followed for periods of from eight months to eight years. Careful selection of donors is mandatory in order to avoid postoperative mortality or morbidity. Anatomic variations which may affect the donor or recipient operations are discussed. There were no deaths, and postoperative complications were usually minor. The most common were atelectasis or pneumonitis or both, pneumothorax, and urinary tract infection. No patients developed permanent renal insufficiency. Compensatory hypertrophy of the remaining kidney resulted in restoration of creatinine clearance and para-aminohippuric acid clearance to two thirds or more of preoperative values. The use of related living donors is justified by the low risk to the donor and the prolongation of life in the recipients.
Author Affiliations
Denver
From the departments of surgery and renal medicine, University of Colorado School of Medicine, Denver (Drs. Penn, Halgrimson, and Starzl), and the Veterans Administration Hospital, Denver (Dr. Ogden). Dr. Ogden is now at the Veterans Administration Hospital, Tucson, Ariz.
Footnotes
Accepted for publication April 15, 1970.
Read before the 27th annual meeting of the Central Surgical Association, Detroit, Feb 27, 1970.
Reprint requests to Department of Surgery, University of Colorado School of Medicine, 4200 E Ninth Ave, Denver 80220 (Dr. Penn).
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