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Clinical and Pathological Analysis of 22 Cases

Hisashi Nikaidoh, MD; Joseph Boggs, MD; Orvar Swenson, MD

AMA Arch Surg. 1970;101(2):245-257.

Abstract
The records of the Children's Memorial Hospital, Chicago, since 1954 included 22 cases of primary tumors of the liver: 11 were malignant hepatomas; 5, benign tumors; and 6, vascular malformations. In the malignant tumor group, five hepatic lobectomies and one wide excision of tumor were performed, as well as two pulmonary lobectomies for metastases. The malignant process was far advanced in five patients and surgical measures were limited to exploration and biopsy. All patients with malignancies died. The longest survival period was three years and four months postsurgery. In contrast to malignancies, all benign lesions were successfully resected, and the patients are alive and well. Tumors of vascular origin were limited to infants, and the lesions often caused significant hemodynamic manifestations. An aggressive approach with roentgenography and radionuclide scanning is advocated for early diagnosis of abdominal masses in pediatric patients. Surgical excision is indicated for all localized liver tumors.

Author Affiliations
Chicago

From the departments of surgery and pathology, the Children's Memorial Hospital, and Northwestern University Medical School, Chicago.

Footnotes
Accepted for publication April 15, 1970.

Read before the 27th annual meeting of the Central Surgical Association, Detroit, Feb 27, 1970.

Reprint requests to the Children's Memorial Hospital, 2300 Children's Plaza, Chicago 60614 (Dr. Nikaidoh).

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