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Alfred Katz, MD; Leo Kaplan, MD; Shaul G. Massry, MD; Robert Heller, MD; David Plotkin, MD; Irving Knight, MD

AMA Arch Surg. 1970;101(5):582-585.

Abstract
Hypercalcemia is frequently observed in patients with breast carcinoma. When the biochemical effects of osteolytic metastases, hormonal therapy, or other pathological states are ruled out, simultaneous hyperparathyroidism must be considered. Six women with breast cancer were found to have anatomic parathyroid gland changes. Two of these patients showed hyperplasia. In one patient all of the parathyroid glands were involved, and in the other patient a single adenomatous gland was removed. The hyperparathyroidism of the latter patient disappeared postoperatively. In four of these patients a single adenoma was found. Their removal in three instances was associated with the disappearance of hyperparathyroidism. The fourth adenoma was found at necropsy.

Author Affiliations
Los Angeles

From the departments of surgery (Drs. Katz and Knight), pathology (Dr. Kaplan), and medicine (Drs. Massry, Heller, and Plotkin, Cedars-Sinai Medical Center, and the Department of Medicine, UCLA School of Medicine (Dr. Massry), Los Angeles. Dr. Massry is established investigator of the American Cancer Society.

Footnotes
Accepted for publication March 11, 1970.

Read before the sectional meeting of the Southern California Chapter of the American College of Surgeons, Coronado, Calif, Jan 16, 1970.

Reprint requests to 8733 Beverly Blvd, Los Angeles 90048 (Dr. Katz).

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