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B. Guy Clendinnen, FRCS; David D. Reeder, MD; Warren D. Davidson, MD; James C. Thompson, MD

AMA Arch Surg. 1970;101(5):596-598.

Abstract
The effect of synthetic human gastrin, pentagastrin, caerulein, pancreozymincholecystokinin (PZ-CCK), and secretin on salivary secretion was tested in dogs with salivary and denervated gastric fistulas. No changes were observed in salivary output. No effect on salivary volume or protein output was found using dosages of the agents which significantly altered gastric-acid output. We conclude that gastrin, PZ-CCK, and secretin are not involved in the physiological control of salivation.

Author Affiliations
Torrance and Los Angeles, Calif

From the departments of surgery and medicine, Harbor General Hospital, Torrance, Calif, and the University of California School of Medicine, Los Angeles. Dr. Clendinnen is now at Southmead Hospital, Bristol, England. Drs. Reeder and Thompson are now at the University of Texas Medical Branch, Galveston.

Footnotes
Accepted for publication June 9, 1970.

Reprint requests to Department of Surgery, University of Texas Medical Branch, Galveston, Tex 77550 (Dr. Thompson).

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