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Streptokinase for Chronic Arterial Occlusive Disease
Michael Hume, MD;
Victor Gurewich, MD;
Duncan P. Thomas, MD;
James B. Dealy, Jr, MD
AMA Arch Surg. 1970;101(6):653-657.
Abstract
Infusions of streptokinase (Streptase [Germany]) in 15 patients with chronic occlusions and stenosis of aorta, iliac, and femoral arteries resulted for some in less claudication, better treadmill performance, return of pulses, and improved appearance of arteriograms. Proximal short stenotic lesions respond more favorably than distal long occlusive ones. Complications of thrombolytic therapy did not preclude surgery where this was indicated.
Author Affiliations
Boston
From the departments of surgery, medicine, and radiology, Tufts University School of Medicine, and the Lemuel Shattuck Hospital, Boston.
Footnotes
Accepted for publication July 30, 1970.
Read before the 18th scientific meeting of the International Cardiovascular Society, Chicago, June 19, 1970.
Reprint requests to Vascular Laboratory, Lemuel Shattuck Hospital, 170 Morton St, Jamaica Plain, Mass 02130 (Dr. Hume).
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