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Donald O. Costley, MD; Paul H. Lorhan, MD

AMA Arch Surg. 1971;103(1):34-35.

Abstract
Two hundred and fifty-three intravenous regional anesthetics (mepivacaine hydrocholoride) were administered to 252 patients requiring operations on the extremities. In the 216 patients where the dose was 4.3 to 8.6 mg in 0.6% solution per kilogram body weight, 212 experienced good results in that no other agent was necessary. Experience with other doses and concentrations showed that the above fluid volume and dose was critical. No toxic complications were experienced.

Author Affiliations
Torrance, Calif

From the departments of anesthesia and surgery, Harbor General Hospital, Torrance, Calif; and the University of California, School of Medicine, Los Angeles. John R. Benfield, MD, sponsored this investigation.

Footnotes
Accepted for publication Feb 26, 1971.

Read before the annual meeting of the Southern California Chapter of the American College of Surgeons, Palm Springs, Calif, Jan 16, 1971.

Reprint requests to 1000 W Carson St, Torrance, Calif 90509 (Dr. Costley).

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