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Report of Two Cases, One With 30-Year Follow-Up

James E. McKittrick, MD; Walter M. Lewis, MD; Wilton A. Doane, MD; Walter H. Gerwig, Jr., MD

AMA Arch Surg. 1971;103(1):57-62.

Abstract
The Peutz-Jeghers syndrome is characterized by intestinal polyposis and mucocutaneous melanin pigmentation. It is inherited as a simple mendelian dominant, but sporadic cases may occur by gene mutation. Polyps are usually present from the gastroesophageal junction to the anus, and are hamartomas with little tendency to malignant degeneration. Recurrent abdominal pain from intussusception is the most frequent symptom, and chronic blood-loss anemia is often pres

Author Affiliations
Santa Barbara, Calif

From the departments of surgery (Drs. McKittrick and Doane) and medicine (Dr. Lewis), Santa Barbara Medical Clinic, and the Department of Surgery, Santa Barbara Cottage-General Hospitals (Dr. Gerwig), Santa Barbara, Calif.

Footnotes
Accepted for publication March 15, 1971.

Read before the annual meeting of the Southern California Chapter of the American College of Surgeons, Palm Springs, Calif, Jan 15, 1971.

Reprint requests to Santa Barbara Medical Clinic, Calle Real at San Marcos Pass Road, PO Box 1200, Santa Barbara, Calif 93102 (Dr. McKittrick).

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