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Richard J. Williams, MD; James G. Chandler, MD; Marshall J. Orloff, MD

AMA Arch Surg. 1971;103(1):8-11.

Abstract
The records, culture material, and autopsy data of 27 patients with Candida septicemia revealed that the overall mortality was 72%, attributed in part to their primary disease as well as to the adverse effects of the Candida sepsis. Twenty-five of the 27 patients received multiple blood transfusions within two weeks of their positive blood cultures. Twenty-five patients had indwelling central venous catheters at the time that their positive Candida blood cultures were drawn. All but one of the entire group received broad-spectrum antibiotics in the two-week period preceding their disseminated candidiasis. These features appeared to be significant predisposing factors and probably account for the increased incidence of Candida septicemia noted in this report.

Author Affiliations
San Diego, Calif

From the Department of Surgery, University of California, San Diego.

Footnotes
Accepted for publication Feb 10, 1971.

Read before the annual meeting of the Southern California Chapter of the American College of Surgeons, Palm Springs, Calif, Jan 16, 1971.

Reprint requests to University Hospital of San Diego County, 225 W Dickinson St, San Diego, Calif 92103 (Dr. Williams).

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