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William M. Toyama, MD; Cesar N. Reyes, MD; Ben R. Lawton, MD; Richard D. Sautter, MD

AMA Arch Surg. 1971;103(2):195-198.

Abstract
Open lung biopsy through a limited thoracotomy was used during the past three years in 11 selected infants and children. Biopsy was used not only for chronic undiagnosed lung diseases but also to accurately confirm suspected serious pulmonary disorders. Adequate lung tissue was obtained in all patients without significant morbidity and without mortality. The diagnoses in our eleven patients were Aspergillus pneumonitis, pulmonary blastomycosis, methotrexate pneumonitis, farmer's lung, visceral larva migrans, pulmonary allergic granulomatosis, Hamman-Rich interstitial fibrosis, idiopathic neonatal pulmonary fibrosis, interstitial pneumonia due to diffuse lupus erythematosis, and chronic bronchitis and bronchiolitis (two cases). In seven of these 11 patients, biopsy revealed a specific diagnosis. The technique permits early accurate diagnosis and treatment.

Author Affiliations
Marshfield, Wis

From the Department of Surgery, Division of Pediatric Surgery (Dr. Toyama), and the departments of pathology (Dr. Reyes) and thoracic and cardiovascular surgery (Drs. Lawton and Sautter), Marshfield (Wis) Clinic and Marshfield Clinic Foundation for Medical Research and Education.

Footnotes
Accepted for publication March 22, 1971.

Read before the 28th annual meeting of the Central Surgical Association, Minneapolis, March 5, 1971.

Reprint requests to Marshfield Clinic Foundation, Marshfield, Wis 54449 (Dr. Toyama).

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