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Rex B. Shafer, MD

AMA Arch Surg. 1971;103(3):411-413.

Abstract
Adenocarcinoma occurred in the aberrant columnar epithelium of the distal esophagus of a 62-year-old man. Symptomatic history was vague but evaluation of a filling defect in the distal esophagus on an upper-gastrointestinal tract series led to esophagoscopy and biopsy. The case emphasizes the unexpected, benign presentation that may be associated with Barrett's esophagus and also draws attention to its association with adenocarcinoma. The experimental evidence includes two theories for the etiology of Barrett's esophagus.

Author Affiliations
Minneapolis

From the Department of Medicine, Section of Gastroenterology, Veterans Administration Hospital, and University of Minnesota, School of Medicine, Minneapolis.

Footnotes
Accepted for publication March 8, 1971.

Reprint requests to Veterans Administration Hospital, 54th Street and 48th Avenue S, Minneapolis 55417 (Dr. Shafer).

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