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  Vol. 103 No. 5, November 1971 TABLE OF CONTENTS
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  PAPERS READ BEFORE THE NINETEENTH SCIENTIFIC MEETING OF THE INTERNATIONAL CARDIOVASCULAR SOCIETY, PHILADELPHIA, JUNE 17-18, 1971
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Electrophysiological Basis for Supraventricular Arrhythmias

Following Surgical Procedures for Aortic Stenosis

Harry L. Bush, Jr., MD; Henry Gelband, MD; Brian F. Hoffman, MD; James R. Malm, MD

AMA Arch Surg. 1971;103(5):620-625.


Abstract



Fifty-eight patients with isolated aortic stenosis who underwent open heart surgery during a three-year period had a 49% incidence of postoperative supraventricular arrhythmias (SVAs). Of the 22 patients under 20 years of age (group A), four (18%) had postoperative SVAs, in contrast to 24 of the 36 patients (66.7%) over 40 years of age (group B). The increase in SVAs in group B was due to increased frequency of atrial flutter-fibrillation. The electrophysiologic characteristics of the right atrial myocardium were normal in group A, but were markedly abnormal in group B. The diffuse spontaneous phase-4 depolarization, local conduction disturbances, and abnormal transmembrane action potential characteristics found in group B could result in multifocal ectopic pacemakers and reentry arrhythmias. Therefore, the majority of the postoperative SVAs in group B may be related to the preoperative cellular abnormalities of their right atrial myocardium.



Author Affiliations



New York

From the Department of Surgery, College of Physicians and Surgeons, Columbia University; and the Surgical Service, Presbyterian Hospital, New York (Drs. Bush and Malm); and the Department of Pharmacology, Columbia University, New York (Drs. Gelband and Hoffman). Dr. Bush is now with the US Naval Hospital, Patuxent River, Md.


Footnotes



Accepted for publication July 6, 1971.

Read before the 19th scientific meeting of the International Cardiovascular Society, Philadelphia, June 18, 1971.

Reprint requests to 622 W 168th St, New York 10032 (Dr. Malm).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Effect of 5-HT4 receptor stimulation on the pacemaker current If in human isolated atrial myocytes
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ABSTRACT | FULL TEXT  

Atrial Pacing Following Open-Heart Surgery
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Arch Surg 1972;105:26-29.
ABSTRACT  





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