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Experience With Candida Infections in the Burn Patient
Bruce G. MacMillan, MD;
Edward J. Law, MD;
Ian A. Holder, PhD
AMA Arch Surg. 1972;104(4):509-514.
Abstract
A review of 427 acutely burned patients reveals that Candida organisms were cultured in 271 patients. The organism was found in the wound in 233 patients and in the urine in 131. Positive blood cultures were present in 22 instances. Disseminated candidiasis was demonstrated at autopsy in 14 of the 65 patients who died. The presence of the organism in the wound may not be of clinical significance, but disseminated systemic infection does occur in a significant number of cases. Discontinuing antibiotic therapy, the removal of intravenous catheters, and, where appropriate, intravenous administration of amphotericin B is advised. While Candida albicans has long been recognized as a pathogen, other species of Candida are also capable of causing systemic disease.
Author Affiliations
Cincinnati
From the Shriners Burns Institute, Cincinnati Unit, and the departments of surgery and microbiology, University of Cincinnati College of Medicine.
Footnotes
Accepted for publication Dec 7, 1971.
Reprint requests to Shriners Burns Institute, Cincinnati 45219 (Dr. MacMillan).
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