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Alan B. Gazzaniga, MD; Allan F. Pacela, ScD; Robert H. Bartlett, MD; Tamar R. Geraghty, RN

AMA Arch Surg. 1972;104(4):515-519.

Abstract
Impedance rheography in conjunction with a respiratory maneuver has proven to be useful in the detection of deep venous thrombosis of the legs. In a study of 25 normal volunteers, there were no changes in base-line impedance of less than 0.19% following deep inspiration. Two hundred fortyfive patients were studied; 45 patients had responses at or below 0.19%, and in 40 cases, deep venous thrombosis was proven or strongly suspected. In a prospective study of 64 patients, deep venous thrombosis was diagnosed six times and confirmed by venography in each case. However, four patients exhibited a false-positive result which appears to be a significant limitation of the method. Preliminary studies have shown that variation in the respiratory maneuver may eliminate the false-positive responses.

Author Affiliations
Irvine, Calif

From the Department of Surgery, University of California, Irvine, Calif. Sponsored by John E. Connolly, MD.

Footnotes
Submitted for publication Nov 22, 1971.

Read before the 79th annual meeting of the Western Surgical Association, Portland, Ore, Nov 19, 1971.

Reprint requests to Department of Surgery, University of California, Irvine, Calif 92664 (Dr. Gazzaniga).

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