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A Critical Reappraisal

John C. German, MD; Telford E. Wooley, MD; Bruce Achauer, MD; David W. Furnas, MD; Robert H. Bartlett, MD

AMA Arch Surg. 1972;104(6):806-808.

Abstract
Early use of porcine skin and mafenide acetate (Sulfamylon Cream) in burn wound care was reported to produce early eschar separation and decrease burn sepsis and pain. Critical evaluation of 20 patients was performed comparing xenograft and mafenide to mafenide alone on the same or similar burn in acute burn surface management with use of the patient as his own control. No difference was found in the interval to eschar separation and healing or autografting. Similarly, no difference was noted between the two treatment areas by skin biopsy or incidence of burn wound infection.

Author Affiliations
Orange, Calif

From the Department of Surgery, University of California, Irvine; and the Burn Unit, Orange (Calif) County Medical Center.

Footnotes
Accepted for publication Feb 15, 1972.

Read before the annual meeting of the Southern California Chapter of the American College of Surgeons, Santa Barbara, Calif, Jan 14,1972.

Reprint requests to Department of Surgery, University of California, Irvine, Calif 92664 (Dr. German).

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