This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (12)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Effect of Oxyphenbutazone, Proteolytic Enzymes From Carica Papaya, and Dextran 40

Brij M. L. Kapur, MS, FRCS, FICS, MAMS; Surinder M. Gulati, MS; Janak R. Talwar, MS

AMA Arch Surg. 1972;105(5):761-764.

Abstract
Peritoneal adhesions were produced in 20 rabbits and 35 monkeys by traumatizing the cecum and corresponding parietal peritoneum. Adhesions were classified into six grades, depending on the extent and density. Combined therapy with oxyphenbutazone, proteolytic enzymes from carica papaya, and dextran 40 after lysis of adhesions reduced the reformation of peritoneal adhesions significantly, and the percentage reduction was greatest as compared to the individual use of the drugs. It is emphasized that the role of any therapy in peritoneal adhesions should be evaluated only by the decrease in the reformation of adhesions after lysis.

Author Affiliations
New Delhi, India

From the Department of Surgery, All-India Institute of Medical Sciences, New Delhi.

Footnotes
Accepted for publication June 15, 1972.

Reprint requests to Department of Surgery, All-India Institute of Medical Sciences, New Delhi 16, India (Dr. Kapur).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?