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Ernest W. Carpenter, MD; S. Martin Lindenauer, MD

AMA Arch Surg. 1973;106(1):75-78.

Abstract
Segments of arteries and veins were interposed in canine carotid arteries as isografts and allografts. The dogs were given azathioprine and prednisone for immunosuppression. In this study immunosuppressive drugs did not significantly alter the gradual deterioration and necrosis of allograft arteries and veins. The allograft vessels failed due to rejection-induced thrombosis that was not altered by immunosuppression.

Author Affiliations
Ann Arbor, Mich

From the Department of Surgery, Section of General Surgery, University of Michigan and Veterans Administration Hospital, Ann Arbor.

Footnotes
Accepted for publication Aug 22, 1972.

Reprint requests to 2215 Fuller Rd, Ann Arbor, Mich 48105 (Dr. Lindenauer).

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