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III. Accelenrated Fracture Healing Through Soluble Heterologous Collagen

Jürgen Benfer, MD; Hansjürgen Struck, PhD

AMA Arch Surg. 1973;106(6):838-842.

Abstract
Wedge-shaped fractures of the tibiae of rats and dogs were locally treated with soluble collagen of pigskin. As a result of this, significantly higher stability levels of the fracture callus were achieved in a shorter time than in controls. Earlier formation of the callus was proved histologically. The serum determinations indicated a mineral deposit on the protein matrix that occurred much sooner than in the control fractures.

Author Affiliations
Cologne, Germany

From the Biochemical Division, Second Department of Surgery, University of Cologne, Germany.

Footnotes
Accepted for publication Dec 15, 1972.

Reprint requests to Biochemische Abteilung an der Chirurgischen, Universitätsklinik, 5 Köln-Merheim, Ostmerheimer Strasse 200, Germany (Dr. Struck).

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