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Combined Isotope Venography and Lung ScanningA New Diagnostic Approach to Thromboembolism
James S. T. Yao, MD, PhD;
Robert E. Henkin, MD;
Julius Conn, Jr., MD;
James L. Quinn, III, MD;
John J. Bergan, MD
AMA Arch Surg. 1973;107(2):146-151.
Abstract
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Venography was performed on 44 patients by injecting radionuclide into a foot vein below an ankle tourniquet and performing rapid-sequence scintiphotography of venous flow in the calves, thighs, and abdomen. A lung scan was also obtained with use of human serum albumin microspheres labeled with Tc 99m. Standard contrast venography was done on 34 of the limbs. There was good correlation between the results from contrast and those from radionuclide venography (89%). Thirteen (39%) of the 33 patients with an abnormal radionuclide venogram had an abnormal lung scan, indicating pulmonary emboli. Of six patients who had pulmonary embolism but clinically silent legs, five had abnormal vein scans. Seven patients with abnormal venograms had abnormal lung scans, suggesting pulmonary emboli, even though they were asymptomatic in both areas. This method seems ideal for detection of the "silent embolus" and is of particular value in understanding the natural progress of the thrombotic process.
Author Affiliations
Chicago
From the departments of surgery and nuclear medicine, Northwestern University Medical School, Chicago.
Footnotes
Accepted for publication March 30, 1973.
Read before the 30th annual meeting of the Central Surgical Association, Toronto, Feb 22, 1973.
Reprint requests to 393 E Chicago Ave, Chicago 60611 (Dr. Yao).
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