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Teuvo K. I. Larmi, MD; Pentti Kärkölä, MD; Hans-Erik Klintrup, MD; Erkki Heikkinen, MD

AMA Arch Surg. 1974;108(2):178-183.

Abstract
Ligation of the hepatic artery without complete dissection of the liver was performed on eight patients with nonresectable hepatic tumors. Three patients had a marked preoperative clinical and chemical obstructive, intrahepatic jaundice, which disappeared postoperatively. Relief of pain and decrease of enlarged liver were initially noticed in seven patients. Hepatic sepsis was a serious complication with fatal outcome in one nonjaundiced man. The hypoxic necrosis of tumors resulting in a remission of symptoms in the survivors and the disappearance of cholestasis in three jaundiced patients was, however, temporary. After two to six months, the jaundice and other symptoms recurred. The conclusion is drawn that a prolonged life expectancy is perhaps not obtained, but a worthwhile, symptomatic improvement and palliative effect can be achieved by hepatic artery ligation.

Author Affiliations
Oulu, Finland

From the Department of Surgery, University Central Hospital, Oulu, Finland.

Footnotes
Accepted for publication Aug 16, 1973.

Reprint requests to Department of Surgery, Oulu University Central Hospital, Kirkkokatu 11 A 25, 90100 Oulu 10, Finland (Dr. Larmi).

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