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Symmetrical Peripheral Gangrene
John N. Goodwin, MD;
Thomas V. Berne, MD
AMA Arch Surg. 1974;108(6):780-784.
Abstract
Four patients with acute medical illnesses developed peripheral symmetrical gangrene. All were seen in one hospital within a six-month period. There was no evidence of significant proximal arterial occlusion. Hypotension and poor tissue perfusion were present in each case. There was associated sepsis in three. Diffuse intravascular coagulation was documented in one patient and suspected in another. All patients demonstrated some degree of acute renal failure, and myoglobinuria was noted in two. All patients ultimately died. An appreciation of the seriousness of the etiological factors in patients with peripheral symmetrical gangrene will direct therapeutic efforts toward correction of the underlying disorder and avoid unnecessary angiography or surgical intervention.
Author Affiliations
Los Angeles
From the Los Angeles County-University of Southern California Medical Center and the Department of Surgery, University of Southern California School of Medicine, Los Angeles.
Footnotes
Accepted for publication Feb 13, 1974.
Read before the annual meeting of the Southern California Chapter of the American College of Surgeons, Palm Springs, Calif, Jan 18, 1974.
Reprint requests to Department of Surgery, Los Angeles County-University of Southern California Medical Center, 1200 N State St, Los Angeles, CA 90033 (Dr. Berne).
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