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Human Amniotic Membrane as a Physiologic Wound Dressing
Guillermo Colocho, MD;
William P. Graham, III, MD;
Arthur E. Greene, PhD;
Dale W. Matheson, PhD;
Dennis Lynch, MD
AMA Arch Surg. 1974;109(3):370-373.
Abstract
In 65 patients, split-thickness donor sites were covered with amniotic membrane. Amniotic membrane was used to dress partialthickness burns in 42 patients. In rats, open wounds were covered with amnion and in others it was placed in a subcutaneous pocket. The amnion acted as a comfortable and effective wound dressing. None of the biopsy specimens, however, showed vascularization of the amnion by the host.
Author Affiliations
From the General Clinical Research Center of the Graduate Hospital, Philadelphia (Drs. Colocho and Lynch); the departments of surgery and anatomy, Milton S. Hershey Medical Center of the Pennsylvania State University, Hershey, Penn (Drs. Graham and Matheson); and the Institute for Medical Research, Camden, NJ (Dr. Greene).
Footnotes
Accepted for publication July 20, 1973.
Read before the Plastic Surgery Research Council, Indianapolis, May 1970.
Reprint requests to Hershey Medical Center, Pennsylvania State University, Hershey, PA 17033 (Dr. Graham).
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