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Effect of Varying Percentage of Bypass Flow Rate

John L. Pennock, MD; William S. Pierce, MD; G. Allen Prophet; John A. Waldhausen, MD

AMA Arch Surg. 1974;109(5):635-641.

Abstract
Myocardial oxygen utilization during left heart bypass was studied in a preparation where a mean aortic pressure of 75 mm Hg and a heart rate of 100 beats per minute were kept constant. The relationship of reduction of myocardial oxygen consumption (MVO₂) as bypass increased was nonlinear. A partial bypass flow as high as 80% produced a decrease in MVO₂ of only 15% from controls. Thereafter, MVO₂ decreased rapidly to a maximum reduction of 50% from controls with complete left ventricular bypass with left ventricular decompression.

This study indicates that the maximum benefit in salvaging marginal ischemic muscle with the use of left ventricular bypass would be expected to occur with complete left ventricular bypass and left ventricular decompression.

Author Affiliations
From the Department of Surgery, College of Medicine; and the Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pa.

Footnotes
Accepted for publication July 12, 1974.

Read before the 22nd scientific meeting of the International Cardiovascular Society, Chicago, June 21, 1974.

Reprint requests to College of Medicine, Department of Surgery, Milton S. Hershey Medical Center, Hershey, PA 17033 (Dr. Pierce).

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