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Horace C. Stansel, Jr, MD; Dov B. Nudel, MD; Michael A. Berman, MD; Norman S. Talner, MD

Arch Surg. 1975;110(11):1397-1400.

Abstract
• Reported clinical experiences with prosthetic valve replacement in children have suggested a high operative mortality. We placed 25 valves in 24 children with one operative death. There has been one late death related to pacemaker malfunction, but the remainder of the patients have generally done extremely well. The children have not undergone elective anticoagulation, and the long-term embolism rate has not exceeded the incidence of systemic embolization in adults who have been controlled on warfarin sodium (Coumadin) therapy. The objective of prosthetic valve replacement is myocardial preservation. We believe that valve replacement with currently available prostheses should be undertaken in any child with valvular malfunction who is not well controlled with good medical management.

(Arch Surg 110:1397-1400, 1975)

Author Affiliations
From the Department of Cardiothoracic and Cardiovascular Surgery, Yale University School of Medicine, New Haven, Conn.

Footnotes
Accepted for publication July 18, 1975.

Read before the 23rd scientific meeting of the International Cardiovascular Society, Boston, June 20, 1975.

Reprint requests to Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510 (Dr Stansel).

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