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  Vol. 110 No. 12, December 1975 TABLE OF CONTENTS
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  EXPERIMENTAL SURGERY
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Host Response to Implanted Dacron Grafts

A Comparison Between Mesh and Velour

Nicholas L. Tilney, MD; Paul J. Boor, MD

Arch Surg. 1975;110(12):1469-1472.


Abstract

• Segments of open Dacron mesh grafts were subcutaneously implanted in rats and harvested for a period of up to 12 weeks after operation at serial intervals. The gross and histologic events of the host response to the external surface were compared to that of segments of low-porosity Dacron velour implanted in a similar fashion. Mature collagen, generously vascularized with new capillaries, was noted throughout the mesh within three to four weeks, while a tightly bonded inner fibrous layer had formed from the surrounding tissues. Major segments of velour floated in amorphous caseous material for up to five weeks. These pools of debris with their concomitant inflammatory response slowly resolved during a ten-week period. This prolonged healing may contribute to eventual graft closure by progressive fibrosis and extrinsic contracture.

(Arch Surg 110:1469-1472, 1975)



Author Affiliations

From the departments of surgery (Dr Tilney) and pathology (Dr Boor), Peter Bent Brigham Hospital and Harvard Medical School, Boston.


Footnotes

Accepted for publication March 4, 1975.

Reprint requests to Department of Surgery, Peter Bent Brigham Hospital, 721 Huntington Ave, Boston, MA 02115 (Dr Tilney).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Management of Draining Wounds in Vascular Surgery
Schaberg et al.
VASC ENDOVASCULAR SURG 1982;16:213-218.
ABSTRACT  





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