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Michael Cherington, MD; Stanley Ginsburg, MD

Arch Surg. 1975;110(4):436-438.

Abstract
Botulism occurring in patients with wounds has been thought of as a rare disease. A patient with a lacerating wound of his hand and wrist and an avulsion of his fourth finger developed diplopia, dizziness, and slurred speech one week later, followed by generalized weakness and difficulty in swallowing. Repetitive nerve stimulation studies showed signs of neuromuscular block consistent with the diagnosis of botulism. Results of bacteriologic and immunologic tests were not revealing, but the subsequent course of progressing, and retrogressing, bulbar signs and symptoms with eventual nearcomplete recovery confirmed the diagnosis. Increasing awareness and employment of electrophysiologic studies are uncovering increasing numbers of cases.

Author Affiliations
From the Department of Neurology, University of Colorado School of Medicine, Denver.

Footnotes
Accepted for publication Oct 11, 1974.

Read in part before the second Industrial and Environmental Neurology Congress, Prague, Sept 26, 1974.

Reprint requests to Department of Neurology, University of Colorado Medical Center, 4200 E Ninth Ave, Denver, CO 80220 (Dr. Cherington).

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