This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

MAJ Albert J. Czaja, MC; MAJ Joseph C. McAlhany, Jr., MC; MAJ Willard A. Andes, MC; COL Basil A. Pruitt, Jr., MC

Arch Surg. 1975;110(5):600-605.

Abstract
Diffuse erosive "gastritis" was discovered as early as five hours postinjury in 45 of 54 burn patients (83.5%) evaluated by gastroduodenoscopy. Acute ulcers were identified in 14 patients (26%); concomitant duodenal disease was present in 34 patients (76%). Microvascular fibrin thrombi were not demonstrated even though five patients had disseminated intravascular coagulation. Seven patients were examined before nasogastric intubation; four, with a mean burn size of 59.6% total body surface, had diffuse "gastritis." Low total serum protein levels were measured in 81% of tested patients, but were not predictive of mucosal disease. Hemorrhage followed the clinical deterioration of six patients (11.1%); one ulcer perforated. Whereas coagulation abnormalities, nasogastric intubation, and hypoproteinemia may augment mucosal injury, the morphologic and histologic examinations of the lesions suggested a primary ischemic cause resulting from the opening of submucosal shunts or local vasoconstriction.

Author Affiliations
USA; USA; USA; USA

From the US Army Institute of Surgical Research, Brooke Army Medical Center, Fort Sam Houston, Tex.

Footnotes
Accepted for publication Dec 15, 1974.

Read before the 82nd annual meeting of the Western Surgical Association, San Francisco, Nov 22, 1974.

The opinions or assertions contained herein are the private views of the authors and are not to be considered as official or as reflecting the views of the Department of the Army or the Department of Defense.

Reprint requests to US Army Institute of Surgical Research, Brooke Army Medical Center, Fort Sam Houston, TX 78234 (Dr. Czaja).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Gastric Acid Secretion and Acute Gastroduodenal Disease After Burns
Czaja et al.
Arch Surg 1976;111:243-245.
ABSTRACT