This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (17)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

IV. The Enzyme Content of Commercial Pancreatic Supplements

Frederick W. Pairent, PhD; John M. Howard, MD

Arch Surg. 1975;110(6):739-741.

Abstract
Comparative in vitro analyses of 14 commercial pancreatic supplements were performed as to their protease, trypsin, trypsinogen, amylase, and lipase contents. Extreme variation was found in the individual enzyme activities of the various preparations tested. Pancrelipase (Cotazym) had at least double the activity of all enzymes tested in comparison to the next most potent preparation. Two preparations were practically void of amylase activity and had very low lipase activity. Although trypsin and trypsinogen activities were quite variable, protease activity (toward hemoglobin) was the least variable factor tested.

Author Affiliations
From the Department of Biological Chemistry, Hahnemann Medical College, Philadelphia (Dr. Pairent), and the Department of Surgery, Medical College of Ohio, Toledo (Dr. Howard).

Footnotes
Accepted for publication Dec 3, 1974.

Reprint requests to Department of Surgery, Medical College of Ohio, Arlington and South Detroit avenues, Toledo, OH 43614 (Dr. Howard).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?