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John R. Brooks, MD; Dariush Kia, MD; Alejandro A. Membreno, MD

Arch Surg. 1975;110(7):822-825.

Abstract
Two hundred sixty-five patients who underwent vagotomy and pyloroplasty for duodenal ulcer disease were observed postoperatively, 220 for two to ten years, with an average follow-up of five years.

Vagotomy and pyloroplasty carried a higher overall recurrence rate (3.6%) than did subtotal gastrectomy and vagotomy (1%), largely because of the high ulcer recurrence rate more than two years after operation for massive bleeding (9.2%) rather than that following elective operation (1.8%). Thirty-five percent of these patients with recurrent ulcers did well with medical management and did not require a second operation.

The mortality of vagotomy and pyloroplasty for a massively bleeding ulcer (11%) was less than that following subtotal gastrectomy (21%). The mortality of elective vagotomy and pyloroplasty was 1%.

Author Affiliations
From the Surgical Department, Harvard Medical School at the Peter Bent Brigham Hospital, Boston.

Footnotes
Accepted for publication Dec 26, 1974.

Reprint requests to 721 Huntington Ave, Boston, MA 02115 (Dr. Brooks).

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