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George Drivas, MD; Leslie Pulman; P. R. Uldall, MD, FRCP; E. Nigel Wardle, MA, MD, MRCP

Arch Surg. 1976;111(12):1368-1371.

Abstract
• Using the clearance of microaggregated iodinated human serum albumin reticuloendothialial system (RES) phagocytic function was tested in 48 long-term renal allograft recipients and was found to be defective at the time of testing in 70%. Depression of RES phagocytosis could be related to total steroid dosage in the previous year and to the patients liability to bacterial infections. Evidence from this test does not suggest an immunosuppressive effect of cytomegalovirus. However, three patients are discussed who have developed chronic active hepatitis that is not due to type B virus.

(Arch Surg 111:1368-1371, 1976)

Author Affiliations
From Wellcome Research Laboratories, Department of Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, England.

Footnotes
Accepted for publication June 30, 1976.

Reprints not available.

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