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Bengt Lindberg, MD; Nils Darle, MD

Arch Surg. 1976;111(12):1379-1383.

Abstract
• The effect of intravenous injection of 50 µg/kg of glucagon on the hepatic circulation of the pig was studied in 12 animals. Glucagon caused an arterial pressure reduction of 11 mm Hg after two minutes and 7 mm Hg after ten minutes. The portal pressure and blood flow were not altered. The superior mesenteric arterial flow decreased by 12%. The hepatic arterial blood flow increased by 80% after two minutes and by 58% after ten minutes. There was no difference in response when anesthesia was achieved with small intravenous doses of thiopental (Pentothal) sodium or 70% nitrous oxide in oxygen and tubocurarine chloride.

(Arch Surg 111:1379-1383, 1976)

Author Affiliations
From the Department of Surgery I and III, Sahlgrenska sjukhuset, University of Göteborg (Sweden).

Footnotes
Accepted for publication July 26, 1976.

Reprint requests to Department of Surgery III, Sahlgrenska, S-413 45 Göteborg, Sweden (Dr Lindberg).

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