Fat overload with a 10% soybean oil emulsion
R. P. Belin, B. A. Bivins, J. Z. Jona and V. L. Young
A 10% soybean oil emulsion (Intralipid) has been demonstrated to be an
effective means of delivering an adequate caloric intake via a peripheral
vein. This emulsion has generally been considered safe and free of
significant complications. This is a report of a child who initially
thrived on this intravenously administered fat emulsion, then suddenly
developed a lifethreatening intolerance to the infusion, which appeared to
be the "fat overload syndrome." This syndrome, seen frequently with earlier
fat emulsions, has not been reported previously as a complication of the
10% soybean oil emulsion.
