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Observations on Effects of Prophylactic Antibiotics

Maxwell Finland, MD; John E. McGowan, Jr, MD

Arch Surg. 1976;111(2):143-145.

Abstract
• In a "spot survey" to determine prevalence of nosocomial infections in the Surgical Services of Boston City Hospital in January 1972, the use of antibiotics prophylactically did not significantly affect the occurrence of infections either in patients who had undergone surgery or in those who had not at the time of the survey. Among both groups, whether they had acquired infections or not, the use of antibiotics for prophylaxis did not affect the duration of hospitalization up to the time of the survey. In another study (August through October 1971) of the incidence of infections among patients admitted to the Orthopedic Service of the same hospital, the incidence of infections was the same in patients who received antibiotics prophylactically and in those who did not receive any during their period of hospitalization.

(Arch Surg 111:143-145, 1976)

Author Affiliations
From the Epidemiology Unit, Channing Laboratory, Boston City Hospital and the Department of Medicine, Harvard Medical School, Boston. Dr Finland is a Distinguished Physician, US Veterans Administration. Dr McGowan is now with Grady Memorial Hospital, Atlanta.

Footnotes
Accepted for publication Aug 15, 1975.

Read in part before the Third Symposium on Control of Surgical Infections of the Pre- and Post-operative Care Committee of the American College of Surgeons, Washington, DC, Jan 10, 1972.

Reprint requests to Channing Laboratory, Boston City Hospital, Boston, MA 02118 (Dr Finland).

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