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Agustin Florian, MD; Lawrence H. Cohn, MD; Gustave J. Dammin, MD; John J. Collins, Jr, MD

Arch Surg. 1976;111(3):267-270.

Abstract
• Conduits of expanded, fibrillated polytetrafluoroethylene (PTFE [Gore-tex]) have been evaluated as small vessel prostheses in dogs during a 6-month period. A configuration of high porosity and low density, long fibril Gore-tex was found to yield the best patency in canine arteries (femoral and carotid) and veins (femoral) as compared with more dense, less porous PTFE with shorter fibrils. Host tissue reaction showed minimal inflammation, excellent infiltration, and formation of a smooth neointima, which suggested satisfactory acceptance of the prosthesis.

(Arch Surg 111:267-270, 1976)

Author Affiliations
From the departments of surgery (Drs Florian, Cohn, and Collins) and pathology (Dr Dammin), Harvard Medical School and Peter Bent Brigham Hospital, Boston.

Footnotes
Accepted for publication Oct 10, 1975.

Reprint requests to Department of Surgery, Harvard Medical School, Peter Bent Brigham Hospital, 721 Huntington Ave, Boston, MA 02115 (Dr Cohn).

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