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Albert E. Yellin, MD; Richard M. Dwyer, MD; John R. Craig, MD, PhD; Michael Bass, PhD; Joel Cherlow, PhD

Arch Surg. 1976;111(7):750-755.

Abstract
• An argon-ion laser, coupled to a flexible fiberoptic endoscope, was used to photocoagulate experimentally produced bleeding gastric ulcers in dogs. Argon-ion laser phototherapy rapidly and effectively achieved hemostasis in all bleeding ulcers. Bleeding arteries up to 2 mm in diameter were photocoagulated. Intact normal gastric mucosa was exposed to laser energy for varying periods of time to determine if transmural photothermal injury occurred. Exposure for greater than 15 seconds at 1.0 w of throughput power caused microscopical evidence of transmural injury. Healed, laser-treated ulcers could not be differentiated from nontreated control ulcers or normal stomach one month after injury. The Beer law and the heat-transfer factors relating to soft tissues are discussed. The coupled argon-ion laser-endoscope may be a safe tool to treat self-limited superficial bleeding gastric lesions.

(Arch Surg 111:750-755, 1976)

Author Affiliations
From the departments of surgery (Dr Yellin), medicine (Dr Dwyer), and pathology (Dr Craig), University of Southern California School of Medicine, and the Center for Laser Studies (Drs Bass and Cherlow), University of Southern California, Los Angeles. Dr Dwyer is now with the Department of Medicine, University of California at Los Angeles School of Medicine and the Harbor General Hospital, Torrance, Calif.

Footnotes
Accepted for publication Feb 6, 1976.

Read before the annual meeting of the Southern California Chapter of the American College of Surgeons, Newport Beach, Calif, Jan 17, 1976.

Reprint requests to the Department of Surgery, University of Southern California School of Medicine, 1200 N State St, Room 9420, Los Angeles, CA 90033 (Dr Yellin).

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