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Robert Wylin, MD; John Schneider, MD

Arch Surg. 1976;111(7):818-821.

Abstract
• Improved factor VIII preparations have made major surgery feasible for hemophiliac patients, as well as increasing their survival. In a hemophiliac undergoing prostatectomy, the effects of local or systemic fibrinolysis and possible disseminated intravascular coagulation must be considered, in addition to the factor VIII deficiency. We successfully treated an octogenarian with benign prostatic hypertrophy and mild hemophilia during and after suprapubic prostatectomy by infusions of antihemophilic factor (factor VIII) concentrate. Cessation of infusion on the 15th day resulted in bleeding two days later. This ceased after resumption of antihemophilic factor infusion. Tests for abnormal fibrinolysis and fibrin split products gave negative results.

(Arch Surg 111:818-821, 1976)

Author Affiliations
From the departments of pathology (Dr Wylin) and medicine (Dr Schneider), Harper Hospital and Wayne State University School of Medicine, Detroit.

Footnotes
Accepted for publication Dec 23, 1975.

Reprint requests to Department of Pathology, United Hospitals of Detroit, 3990 John R. St, Detroit, MI 48201 (Dr Wylin).

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