Neoplasms of the large bowel following ureterosigmoidostomy
G. S. Sooriyaarachchi, R. O. Johnson and P. P. Carbone
A poorly differentiated adenocarcinoma of the rectum developed in a
43-year-old man 37 years after ureterosigmoidostomy for epispadias with
urinary incontinence. The review of literature indicates that patients who
have undergone ureterosigmoidostomy have an increased risk for the
development of large bowel neoplasia. The median time interval between the
procedure and the diagnosis of the neoplasm is 21 years, and the median age
at diagnosis is 33 years. The majority of the lesions are malignant and
seem to occur at the site of ureteric anastamosis. The suggested etiologic
mechanisms and the clinical aspects of colonic neoplasia following
ureterosigmoidostomy are discussed.
