This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (18)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Results in 53 Patients

Larry W. Stephenson, MD; Eugene H. Blackstone, MD; Joaquin S. Aldrete, MD

Arch Surg. 1977;112(3):245-249.

Abstract
• Radical pancreaticoduodenectomy for periampullary cancer was performed in 53 patients over a 22-year period. All tumors were adenocarcinomas: 35 patients had adenocarcinoma involving the head of the pancreas, nine, the Vater ampulla, seven, the distal common bile duct, and two, the duodenum. There were nine hospital deaths (17%). The postoperative course was classified as uneventful in 33 patients (62%). Thirty of the 39 patients who left the hospital died later, with evidence of recurrent carcinoma. The actuarial survival rate for the 53 patients was 51% ± 6.9% at one year, 12% ± 4.6% at five years, and 7% ± 3.9% at ten years. Patients surviving 3.5 or more years appeared to have a decrease in their cancer mortality. We discuss actuarial survival rates, according to the location of the tumor. This experience suggests that radical pancreaticoduodenectomy is indicated to remove small, localized periampullary carcinomas in patients who are otherwise in good health.

(Arch Surg 112:245-249, 1977)

Author Affiliations
From the Department of Surgery (Drs Aldrete, Stephenson, and Blackstone), the University of Alabama School of Medicine, and the Surgical Service (Drs Aldrete and Stephenson), the Veterans Administration Hospital, Birmingham, Ala.

Footnotes
Accepted for publication Sept 3, 1976.

Reprint requests to the Department of Surgery, University Station, Birmingham, AL 35294 (Dr Aldrete).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?