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Parathyroid Autotransplantation
Hugh F. Burnett, MD;
Bernard W. Thompson, MD;
Galen L. Barbour, MD
Arch Surg. 1977;112(4):373-379.
Abstract
Autotransplantation of the parathyroid to the forearm has been performed in eight patients following total or subtotal parathyroidectomy. The mass of gland implanted was approximately one half that used in other series. Bilateral simultaneous parathormone levels drawn at three months after autografting reveal higher levels in the autografted arm in every patient examined. Replacement calcium and vitamin D therapy were withdrawn from two patients within eight months after transplant, and it is anticipated that all patients will be off maintenance at 12 months. Electron and light microscopy of grafted tissue has revealed viable glands with intracellular secretory granules, many mitochondria, and little fat. Indications for autotransplantation include patients with refractory renal osteodystrophy, reoperations for primary hyperparathyroidism, and extensive extirpative cancer surgery of the head and neck.
(Arch Surg 112:373-379, 1977)
Author Affiliations
From the Surgical (Drs Burnett and Thompson) and Medical (Dr Barbour) Services, Veterans Administration Hospital, and the Departments of Surgery (Drs Burnett and Thompson) and Medicine (Dr Barbour), University of Arkansas for Medical Sciences, Little Rock.
Footnotes
Accepted for publication Dec 8, 1976.
Read before the 84th annual meeting of the Western Surgical Association, Coronado, Calif, Nov 15, 1976.
Reprint requests to Surgical Service, Veterans Administration Hospital, 300 E Roosevelt Rd, Little Rock, AR 72206 (Dr Burnett).
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