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Sister Mary Ann Lou, MD; Ashis K. Mandal, MD; Joseph L. Alexander, MD; Haragopal Thadepalli, MD

Arch Surg. 1977;112(8):965-967.

Abstract
• Using the modern anaerobic transport media and meticulous culture techniques, 74 patients undergoing biliary tract surgery were studied. The biliary system was found to be sterile in 58 patients (78%). Fifteen patients had 35 isolates of aerobic and facultative bacteria. The most common ones were Klebsiella, Enterococcus, and Escherichia coli. The only anaerobe isolated was Clostridium perfringens. Eight of 17 patients (47%) with acute cholecystitis and five of 49 patients (10%) with chronic cholecystitis, harbored bacteria in the biliary system. This study suggests that anaerobes are rare in the human biliary system; therefore, if antibiotic therapy is considered, aerobic coverage should suffice.

(Arch Surg 112:965-967, 1977)

Author Affiliations
From the Departments of Surgery (Drs Lou, Mandal, and Alexander) and Medicine (Dr Thadepalli), Charles R. Drew Postgraduate Medical School, the University of California at Los Angeles School of Medicine, Martin Luther King, Jr, General Hospital (Drs Lou, Mandal, and Alexander), and the University of Southern California School of Medicine, Martin Luther King, Jr, General Hospital (Dr Thadepalli).

Footnotes
Accepted for publication Feb 22, 1977.

Read before the annual meeting of the Southern California Chapter of the American College of Surgeons, Palm Springs, Calif, Jan 14, 1977.

Reprint requests to Department of Surgery, Martin Luther King, Jr, General Hospital, 12021 S Wilmington Ave, Los Angeles, CA 90059 (Dr Lou).

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