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Use of Tolonium Chloride in the Diagnosis of Malignant Gastric Ulcers
Shamai Giler, MD;
Uri Kadish, MD;
Israel Urca, MD
Arch Surg. 1978;113(2):136-139.
Abstract
• Peroral staining with tolonium chloride (toluidine blue) was performed in 45 patients with suspected gastric ulcer disease. During endoscopy, 19 of 21 malignant ulcers and one of 15 benign ulcers were stained. Following surgery, 18 of 21 malignant ulcers found in the surgical specimens were stained. Eleven patients with benign ulcers underwent surgery and none of these ulcers were found to be stained in the surgical specimens. Normal gastric mucosa and areas of gastritis appeared unchanged. The data suggest that tolonium chloride staining prior to endoscopy or surgery seems to be helpful in differentiating between minute benign and malignant gastric ulcers.
(Arch Surg 113:136-139, 1978)
Author Affiliations
From the Department of Surgery B and the Gastroenterology Unit, Beilinson Medical Center, Petah Tikva, Israel, and the Tel-Aviv (Israel) University Sackler School of Medicine.
Footnotes
Accepted for publication June 30, 1977.
Reprint requests to Department of Surgery B, Beilinson Medical Center, Petah Tikva, Israel (Dr Giler).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Toluidine Blue Staining of the Esophagus: A Useful Adjunct in the Panendoscopic Evaluation of Patients With Squamous Cell Carcinoma of the Head and Neck
Hix and Wilson
Arch Otolaryngol Head Neck Surg 1987;113:864-865.
ABSTRACT
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