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A Progress Report

William W. Monafo, MD; Howard N. Robinson, MD; Toshiharu Yoshioka, MD; Vatché H. Ayvazian, MD

Arch Surg. 1978;113(4):397-401.

Abstract
• Sixteen consecutive patients, nine of whom also had inhalation injury, had burns over 72% body surface area or more. The expected death rate was 94%. In fact, all of the eight patients still alive after 48 hours survived. The early deaths were primarily due to inhalation injury, the treatment of which remains an unsolved problem. A mixture of cerium nitrate and silver sulfadiazine was used for topical wound antisepsis. The wound flora was sparse: 447 of 814 wound-surface cultures were sterile; Gram-negative bacteria were recovered in 13%. This efficacious wound bacteriostasis appeared primarily responsible for the absence of late death.

(Arch Surg 113:397-401, 1978)

Author Affiliations
From the Department of Surgery, St John's Mercy Medical Center, St Louis.

Footnotes
Read before the 85th annual meeting of the Western Surgical Association, Las Vegas, Nov 14, 1977.

Reprints not available.

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