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  Vol. 113 No. 5, May 1978 TABLE OF CONTENTS
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  EXPERIMENTAL SURGERY
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Protective Effects of Adenosine Triphosphate Administration in Burns

Mohamed Sobhi Zaki, MD; John F. Burke, MD; Robert L. Trelstad, MD

Arch Surg. 1978;113(5):605-610.


Abstract

• The effects of intramuscular adenosine triphosphate (ATP) administration after thermal skin injury on the ATP content and morphology of the liver and heart were studied in male Sprague-Dawley rats. The results showed that exogenous ATP injected during the early post-burn period could restore the ATP content of the liver and heart to near normal values and modify the burn-related morphological alterations in the liver.

(Arch Surg 113:605-610, 1978)



Author Affiliations

From the Surgical and Pathology Service of the Shriners Burns Institute and the Massachusetts General Hospital; the Department of Surgery, Harvard Medical School, Boston (Drs Burke and Trelstad); and the Faculty of Medicine, Cairo (Dr Zaki).


Footnotes

Accepted for publication Aug 26, 1977.

Reprint requests to Department of Surgery, Massachusetts General Hospital, Boston, MA 02114 (Dr Burke).



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