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Protective Effects of Adenosine Triphosphate Administration in Burns
Mohamed Sobhi Zaki, MD;
John F. Burke, MD;
Robert L. Trelstad, MD
Arch Surg. 1978;113(5):605-610.
Abstract
The effects of intramuscular adenosine triphosphate (ATP) administration after thermal skin injury on the ATP content and morphology of the liver and heart were studied in male Sprague-Dawley rats. The results showed that exogenous ATP injected during the early post-burn period could restore the ATP content of the liver and heart to near normal values and modify the burn-related morphological alterations in the liver.
(Arch Surg 113:605-610, 1978)
Author Affiliations
From the Surgical and Pathology Service of the Shriners Burns Institute and the Massachusetts General Hospital; the Department of Surgery, Harvard Medical School, Boston (Drs Burke and Trelstad); and the Faculty of Medicine, Cairo (Dr Zaki).
Footnotes
Accepted for publication Aug 26, 1977.
Reprint requests to Department of Surgery, Massachusetts General Hospital, Boston, MA 02114 (Dr Burke).
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