Postsplenectomy thrombocytosis: its association with mesenteric, portal, and/or renal vein thrombosis in patients with myeloproliferative disorders
D. H. Gordon, D. Schaffner, J. M. Bennett and S. I. Schwartz
During the past two years, postoperative thromboses of parts or all of the
splanchnic venous circulation have developed in four of 30 patients with
myeloproliferative disorders who have undergone splenectomy at our
institution. The patients' courses were marked by platelet abnormalities,
both quantitative and qualitative. In an attempt to avoid this
complication, aspirin and low-dose heparin sodium have been administered
and there has been no evidence of thrombosis in the four patients so
managed.
