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Abelardo Arango, MD; J. Lancelot Lester, III, MD; Octavio V. Martinez, PhD; Theodore I. Malinin, MD; Robert Zeppa, MD

Arch Surg. 1979;114(2):154-157.

Abstract
• A technique for intraoperative segmental preparation of the large bowel, using 10% povidone iodine, was evaluated in 25 patients undergoing elective colon resection.

Qualitative and quantitative bacteriology was obtained from the normal bowel content and from segments of colon treated with povidone iodine or normal saline. Forty-five of 50 segments treated with povidone iodine demonstrated no growth, whereas the segments injected with normal saline maintained bacterial counts of 3.5 x 10⁸ colony forming units per milliliter. There were no septic complications in this group of patients and the levels of triiodothyronine and thyroxin remained unchanged despite a substantial absorption of iodine, as demonstrated by proteinbound iodine determinations. Intraoperative segmental preparation of the colon with 10% povidone iodine is a simple technique that may be useful in the enhancement of other methods of bowel preparation by further reducing the endogenous bacterial inoculum at the time of transection of the colon.

(Arch Surg 114:154-157, 1979)

Author Affiliations
From the Department of Surgery, University of Miami School of Medicine, and the Veterans Administration Hospital, Miami.

Footnotes
Accepted for publication June 22, 1978.

Presented at the meeting of the Association of Veterans Administration Surgeons, St Louis, May 1-2, 1978.

Reprint requests to Department of Surgery, University of Miami School of Medicine, PO Box 520875, Miami, FL 33152 (Dr Arango).

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