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Preoperative Chemotherapy for Initially Unresectable Hepatoblastoma in ChildrenSurvival in Two Cases
Keiichi Ikeda, MD;
Sachiyo Suita, MD;
Akira Nakagawara, MD;
Kazuaki Takabayashi, MD
Arch Surg. 1979;114(2):203-207.
Abstract
In two children with hepatoblastoma, response to chemotherapy permitted subsequent surgical resection. Initially, in both patients, the tumor was thought to be unresectable because of size and/or extent. Chemotherapy with vincristine sulfate and cyclophosphamide resulted in substantial reduction in tumor size, and laparotomy for excision was performed after nine months and four months of therapy, respectively.
In case 1, the tumor was localized in the right hepatic lobe and the right hepatic lobectomy was performed. In case 2, the tumor was located in both right and left lobes, but was encapsulated and it was possible to enucleate the tumor with complete gross excision. Both children are living and well without evidence of recurrence of tumor 11 and 23 months after operation.
(Arch Surg 114:203-207, 1979)
Author Affiliations
From the Department of Pediatric Surgery, Kyushu University Hospital, Fukuoka, Japan, (Drs Ikeda, Suita, and Nakagawara), and the Department of Pediatrics, Beppu (Japan) National Hospital (Dr Takabayashi).
Footnotes
Accepted for publication Sept 15, 1978.
Reprint requests to Department of Pediatric Surgery, Kyushu University Hospital, 1-1, 3-chome, Maedashi, Higashi-ku, Fukuoka, Japan.
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ABSTRACT
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