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A Critical Review of 662 Examinations

Carl O. Knutson, MD; Martin H. Max, MD

Arch Surg. 1979;114(4):430-435.

Abstract
• The results of 662 therapeutic and diagnostic colonoscopic examinations were reviewed to assess the morbidity, clinical benefit, diagnostic accuracy, and indications for the procedure, with special emphasis on detection and endoscopic excision of small, occult, invasive cancers. Overall, the frequency of detecting occult lesions (19%), the (89%) ability to clarify questionable radiographic findings, and a substantial reduction in laparotomycolotomy procedures required for removal of colonic polyps (88%), coupled with a low morbidity (3%) and low false-negative examination rate (1%) established colonoscopy as one of the most important advances in the management of colon disease in recent years. Although early experience suggests that small, occult, invasive carcinomas, when properly selected, could be adequately treated by endoscopic excision, larger series and longer follow-up periods are necessary to validate any conclusions regarding the decision to manage these lesions conservatively.

(Arch Surg 114:430-435, 1979)

Author Affiliations
From the Section of Surgical Endoscopy, Department of Surgery, University of Louisville School of Medicine, Health Sciences Center.

Footnotes
Accepted for publication Dec 7, 1978.

Read before the 86th annual meeting of the Western Surgical Association, Scottsdale, Ariz, Nov 14, 1978.

Reprint requests to Department of Surgery, University of Louisville School of Medicine, Health Sciences Center, PO Box 35260, Louisville, KY 40232 (Dr Knutson).

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