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Raphael Walden, MD; Gilbert J. L'Italien; Joseph Megerman, PhD; William M. Abbott, MD

Arch Surg. 1980;115(10):1166-1169.

Abstract
• Clinical results from medium- and small-caliber arterial bypass grafts are unsatisfactory. Since elastic properties of grafts tested experimentally have been correlated with patency results, the compliance of the human femoral artery was compared with grafts currently in use: human saphenous vein (HSV), knitted Dacron (DAC), glutaraldehyde-treated umbilical cord vein (DBM), bovine heterograft, and expanded polytetrafluoroethylene (PTFE). This was correlated with clinical patency data for the different conduits in the femoropopliteal position. Increased patency correlated with a decreasing disparity between host artery and graft compliance. After two years, patency rates of the more compliant materials (HSV, DBM) exceeded 80%, while less than 45% of the incompliant grafts (DAC, PTFE) remained patent. Thus, clinical performance with synthetic grafts might be improved by use of prostheses in which the viscoelastic characteristics match those of arteries more closely.

(Arch Surg 115:1166-1169, 1980)

Author Affiliations
From the General Surgical Services, Massachusetts General Hospital; and the Department of Surgery, Harvard Medical School, Boston.

Footnotes
Accepted for publication May 12, 1980.

Read before the sixth annual meeting of the New England Society for Vascular Surgery, Waterville Valley, NH, Sept 27, 1979.

Reprint requests to Section of Vascular Surgery, Massachusetts General Hospital, Boston, MA 02114 (Dr Abbott).

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