This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Effects of Nitroprusside After Bypass Operations

Ronald C. Hill, MD; W. Randolph Chitwood, Jr, MD; James D. Sink, MD; Jim L. Cox, MD; Andrew S. Wechsler, MD

Arch Surg. 1980;115(5):609-614.

Abstract
• Direct on-line assessment of postoperative ventricular function has not been possible. We assessed the feasibility of using pulse-transit sonomicrometry to measure regional function in man postoperatively. Ultrasonic transducers (3 mm in diameter) were implanted along the minor axis of the left ventricle at midwall depth into a region supplied by a bypass graft. All wires were tunneled subcutaneously. Pressures, ECG, and regional dimensions were monitored in eight patients continuously, and at 48 to 72 hours postoperatively, the effects of sodium nitroprusside were assessed. The transducers were withdrawn with no complications. Nitroprusside was associated with an increase in systolic shortening from 1.60 ± 0.19 to 1.92 ± 0.25 mm and rate of shortening from 12.13 ± 1.85 to 15.34 ± 2.38 mm/s at constant end-diastolic lengths. Using this technique for recording regional dimensions, nitroprusside therapy augmented function at a constant preload.

(Arch Surg 115:609-614, 1980)

Author Affiliations
From the Departments of Surgery, Veterans Administration Hospital and Duke University Medical Center, Durham, NC.

Footnotes
Accepted for publication Oct 30, 1979.

Read in part before the Third Annual Symposium for Continuing Education in Surgery, Association of Veterans Administration Surgeons, Salt Lake City, May 7, 1979.

Reprint requests to Department of Surgery, Veterans Administration Hospital, 508 Fulton St, Durham, NC 27705 (Dr Hill).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Control of Left Ventricular and Proximal Aortic Dimensional Decompensation During Clamping of Descending Thoracic Aorta
Katsamouris et al.
VASC ENDOVASCULAR SURG 1988;22:316-327.
ABSTRACT